get doctor to prescribe azithromycin By definition, uricosuric drugs such as probenecid, benzbromarone, the anti inflammatory drug sulfinpyrazone, the antihypertensive drug losartan, and the loop diuretic furosemide increase urate secretion, whereas antiuricosuric drugs such as pyrazioic acid the metabolite of the antituberculous agent pyrazinamide, nicotinate, and lactate decrease urate secretion